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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2119 | Venetoclax | GDC-0199,ABT 199,ABT-199,ABT199 | BCL , Autophagy |
Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and orally active properties. Venetoclax has a 3-order-of-magnitude lower affinity for Bcl-xL and Bcl-W (Kis=48/245 nM). Venetoclax induces a... | |||
T74015 | Venetoclax N-oxide | ||
Venetoclax N-oxide is an impurity of Venetoclax. Venetoclax (ABT-199; GDC-0199), a highly potent, selective, and orally bioavailable inhibitor of Bcl-2, demonstrates a Ki value of less than 0.01 nM [1]. |