gal2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8456	GALNON		Neuropeptide Y Receptor
	Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties		Neuropeptide Y Receptor
TP1993L	M617 acetate		Neuropeptide Y Receptor
	M617 acetate is a selective agonist of galanin receptor 1 (GAL1). M617 acetate acts through central GAL1, promotes GLUT4 expression, and enhances GLUT4 content in the cardiac muscle of type 2 diabetic rats. The Ki values...		Neuropeptide Y Receptor
TP1994L	M871 acetate		Neuropeptide Y Receptor
	M871 acetate is a selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM at GAL2 and GAL1 receptors, respectively).It blocks pronociceptive effects of GAL2 agonists including AR-M1896.		Neuropeptide Y Receptor
T8559	Galnon TFA(475115-35-6(free base))		Neuropeptide Y Receptor
	Galnon is a novel non-peptide galanin receptor agonist (GAL1 and GAL2 with Ki of 11.7 and 34.1 μM respectively).		Neuropeptide Y Receptor
TP1991L	M 1145 acetate		Neuropeptide Y Receptor
	M1145 acetate, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 acetate shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher af...		Neuropeptide Y Receptor
TP1992L	M40 acetate(143896-17-7 free base)		Neuropeptide Y Receptor
	M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates ...		Neuropeptide Y Receptor
T8963	CYM2503		Neuropeptide Y Receptor
	CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthosteric galanin binding site of the receptor (as measured by ...		Neuropeptide Y Receptor
TP1930L1	Spexin acetate(1370290-58-6 free base)		Neuropeptide Y Receptor
	Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits...		Neuropeptide Y Receptor
TP1994	M871
	Selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM for GAL2 and GAL1 receptors respectively). Blocks the pro-nociceptive effect of GAL2 receptor agonists.
TP1991	M1145	M 1145
	Potent and selective galanin receptor 2 (GAL2) agonist (EC50 = 38 nM, Ki values are 6.55, 497 and 587 nM at GAL2, GAL3 and GAL1 respectively). Has an additive effect on the signal transduction of galanin.
TP1992	M40
	Potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant...
T75819	M1145 TFA
	M1145 TFA, a chimeric peptide, acts as a selective agonist for the galanin receptor type 2 (GAL2), demonstrating a binding affinity (K i ) of 6.55 nM. It exhibits significantly greater selectivity for GAL2, with over 90-...
TP2028	Galanin (1-29)(rat, mouse)	Galanin (1-29) (rat, mouse)
	Non-selective galanin receptor agonist (Ki values are 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.
T75818	Galanin (1-29)(rat, mouse) TFA
	Galanin (1-29)(rat, mouse) TFA acts as a non-selective agonist for galanin receptors, exhibiting affinities (Kis) of 0.98 nM for GAL1, 1.48 nM for GAL2, and 1.47 nM for GAL3, respectively. It possesses an anticonvulsant ...
T73648	Galnon TFA
	Galnon TFA is a selective, non-peptide agonist specifically targeting the galanin receptors GAL1 and GAL2, demonstrating binding affinities (Kis) of 11.7 and 34.1 μM, respectively. This compound exhibits both anticonvuls...
TP1993	M617
	Selective galanin GAL1 receptor agonist (Ki values are 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively). Enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pa...
T75817	M617 TFA
	M617 TFA, a selective galanin receptor 1 (GAL1) agonist, exhibits dissociation constants (Kis) of 0.23 nM for GAL1 and 5.71 nM for GAL2. Through activation of GAL1, M617 TFA enhances GLUT4 expression and content in the c...
TP1930	Spexin
	Potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty ac...
T76002	Spexin TFA
	Spexin TFA, a potent agonist for galanin receptor 2/3 (GAL2/GAL3) with EC50 values of 45.7 and 112.2 nM respectively, shows no significant activity towards galanin receptor 1. As an endogenous peptide promoting satiety, ...
T38109	Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
	Galanin (2-11) amide is a synthetic peptide fragment of the neuropeptide galanin and an agonist of the galanin-2 (GAL2) receptor (EC50= 9.32 nM in a fluorescence imaging plate reader assay).1It selectively binds to the G...