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Search Results for " fzm1 "

2

Compounds

Cat No. Product Name Synonyms Targets
T24076 FzM1 FzM 1,FzM-1 Wnt/beta-catenin
FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2) by binding to an allosteric site on intracellular loop 3 (ICL...
T15363 FzM1.8 Wnt/beta-catenin
FzM1.8 is an allosteric FZD4 agonist with a pEC50 of 6.4. FzM1.8 binds to FZD4, promotes TCF/LEF transcriptional activity in the absence of any WNT ligand, and activates the WNT/β-catenin pathway.
TargetMol