5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11338 | Furamidine | DB75,NSC 305831 | Others |
Furamidine is also a selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 28... | |||
T27395 | Furamidine dihydrochloride | DB 75, DB75, NSC 305831, WR199385,Furamidine HCl | |
Furamidine is a cell-permeable, selective inhibitor of protein arginine methyltransferase 1 (PRMT1). Furamidine binds to strings of AT base pair sequences in DNA′s minor groove. Furamidine targets the enzyme active site ... | |||
T16428 | Pafuramidine | DB289 | Others |
Pafuramidine is an orally bioavailable prodrug of furamidine. It has activity against Pneumocystis pneumonia (IC50 value: 4.5 nM) | |||
T24587 | Pafuramidine maleate | DB-289,DB289,DB 289 | |
Pafuramidine is an orally bioavailable prodrug of formamidine which was developed for the treatment of human African trypanosomiasis. | |||
T64372 | DB722 | Others | |
DB722 is a furamidine analogues with DNA binding activity. DB722 shows antiproliferative activity. |