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Search Results for " ftsz-in-1 "

8

Compounds

Cat No. Product Name Synonyms Targets
T63552 FtsZ-IN-1
FtsZ-IN-1 is a potent FtsZ inhibitor with a quinoline ring and has a strong inhibitory effect on Gram-positive bacteria (MIC: 0.5-8 μg/mL).FtsZ-IN-1 enhances FtsZ polymerization and significantly promotes cell elongation...
T21831 UCM05 G28UCM Fatty Acid Synthase
UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including in cell lines resistant to anti-HER2 drugs [1]. Additionally, it functions as an inhibito...
T74790 FtsZ-IN-7
FtsZ-IN-7 is a potent inhibitor of FtsZ, enhancing FtsZ polymerization while inhibiting its GTPase activity, therefore disrupting bacterial cell division and culminating in bacterial cell death. It exhibits bactericidal ...
T61737 FtsZ-IN-4
FtsZ-IN-4, an orally active inhibitor of FtsZ (filamenting temperature-sensitive mutant Z), demonstrates remarkable antibacterial activity and favorable pharmaceutical properties. With low cytotoxicity (CC 50 >20 μg/mL) ...
T74791 FtsZ-IN-8
FtsZ-IN-8, a potent inhibitor of FtsZ, both promotes FtsZ polymerization and inhibits its GTPase activity, leading to the inhibition of bacterial division and subsequent bacterial cell death. This compound exhibits bacte...
T74789 FtsZ-IN-6
FtsZ-IN-6 is a potent inhibitor of FtsZ, enhancing its polymerization while inhibiting its GTPase activity, thereby obstructing bacterial cell division and causing bacterial cell death. This compound exhibits bactericida...
T74788 FtsZ-IN-5
FtsZ-IN-5 is a potent inhibitor of FtsZ, promoting polymerization while inhibiting its GTPase activity, thereby preventing bacterial division and leading to cell death. It exhibits bactericidal activity without significa...
T61274 PC190723
PC190723 (Compound 2), an inhibitor of the FtsZ bacterial cell division protein, demonstrates potent efficacy with an IC50 value of 55 ng/ml. Additionally, it showcases notable anti-staphylococcal activity, characterized...
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