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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79781 | FPR1 antagonist 1 | ||
Compound 24a, an FPR1 antagonist, demonstrates potent inhibition of the formyl peptide receptor 1 (FPR1) with an IC50 value of 25 nM. It impedes cell proliferation and promotes apoptosis, thereby inhibiting cell growth. ... | |||
T79782 | FPR1 antagonist 2 | ||
Compound 25b, an FPR1 antagonist, exhibits potent inhibition of the formyl peptide receptor 1 with an IC50 of 70 nM. It concurrently hampers cell proliferation and triggers apoptosis, diminishing cell growth and migratio... | |||
T8313 | HCH6-1 | Others | |
HCH6-1 is a competitive Formyl peptide receptor 1 (FPR1) antagonist. | |||
TP1168 | N-Formyl-Met-Leu-Phe-Lys | fMLFK | Others |
N-Formyl-Met-Leu-Phe-Lys (fMLFK) (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) ... | |||
T7484L | WKYMVM 2TFA(187986-17-0(free base)) | Others | |
WKYMVM 2TFA is a N-formyl peptide receptor (FPR1) agonist. | |||
T16449 | PD176252 | Bombesin Receptor | |
PD176252 is a potent BB1 and BB2 antagonist with inhibitory effects on BB1 and BB2 receptors.PD176252 acts as a small molecule GRPR inhibitor and FPR1/FPR2 agonist to inhibit the growth and proliferation of a variety of ... | |||
T40446 | AG-09/1 | Others | |
AG-09/1 is a selective and potent formyl peptide receptor 1 (FPR1) agonist that activates chemotaxis in human neutrophils. | |||
TP1915 | Boc-MLF | Others | |
Antagonist of formyl peptide receptor 1 (FPR1). Reduces superoxide production induced by fMLF with an EC50 of 0.63 μM. Almost completely blocks fMLF-stimulated primary granule exocytosis. | |||
TP1212 | N-Boc-Phe-Leu-Phe-Leu-Phe | Boc-FLFLF | Others |
N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) (Boc-FLFLF) is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin. Boc-Phe-Leu-Phe-Leu-Phe is used extensive... | |||
T8691 | PD 168368 | PD168368 | Bombesin Receptor |
PD 168368 is a novel, potent, competitive and selective nonpeptide neuromodulin B receptor (NMB-R) antagonist with inhibitory effects on the gastrin-releasing peptide receptor (GRPR).PD 168368 is a potent mixed agonist o... | |||
T17005 | FPR Agonist 43 | Others | |
FPR Agonist 43 is a dual agonist of formyl peptide receptor 1 and formyl peptide receptor 2 (FPR2)/ALX. | |||
T21493 | Cyclosporin H | Others | |
Cyclosporin H (CsH), a specific inhibitor of FPR1, inhibited lung inflammation in the ALI models. CsH significantly attenuated MTDs or NFP-induced inflammatory lung injury and activation of MAPK and AKT pathways. Cyclosp... | |||
T26929 | BVT173187 | BVT 173187,BVT-173187 | |
BVT173187 is a neutrophil formyl peptide receptors (FPR1) inhibitor. | |||
T7484 | WKYMVM | Others | |
WKYMVM is a N-formyl peptide receptor (FPR1) agonist. | |||
TP2083 | Ac9-25 | ||
N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. Acts as a formyl peptide receptor 1 (FPR1) ligand and stimulates neutrophil NADPH oxidase activation. | |||
T75815 | WKYMVM-NH2 TFA | ||
WKYMVM-NH2 TFA, a potent agonist for N-formyl peptide receptor (FPR1) and FPRL1/2, activates key leukocyte effector functions including chemotaxis, complement receptor-3 mobilization, and NADPH oxidase activation, as doc... | |||
T39789 | BMS-986235 | BMS-986235,LAR-1219 | Others |
BMS-986235 (LAR-1219) is a selective and orally active agonist of formyl peptide receptor 2 (FPR2) with EC50s of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 can be used in studies about the preventio... | |||
T38227 | Quin C1 | ||
Potent and selective FPR2 agonist (EC50 = 15 nM). Induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts ... | |||
TP1948 | PBP10 | PBP 10 | |
Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro... | |||
T75811 | PBP10 TFA | ||
PBP10, a cell-permeable and selective gelsolin-derived peptide, inhibits formyl peptide receptor 2 (FPR2) over FPR1 [1]. This 10-amino acid (AA) peptide features a rhodamine conjugation at its N terminus, exhibiting bact... |