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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15274 | FEN1-IN-1 | LNT-1 | Others |
FEN1-IN-1 (LNT-1) is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions. | |||
T9743 | FEN1-IN-SC13 | Others | |
FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1) | |||
T8545 | FEN1-IN-4 | FEN1 Inhibitor C2 | Others |
FEN1-IN-4 (FEN1 Inhibitor C2) is an inhibitor of human flap endonuclease-1 (hFEN1) | |||
T40931 | FEN1-IN-2 | FEN1-IN-2 | Others |
FEN1-IN-2 is a selective and potent inhibitor of flap endonuclease 1 (FEN1), inhibits FEN1 and XPG, has potential anticancer activity, and can be used to study DNA damage repair. | |||
T9147 | FEN1-IN-3 | ||
FEN1-IN-3 is a human flap endonuclease-1 ( hFEN1 ) inhibitor that stabilizes hFEN1 with an EC 50 of 6.8 μM . | |||
T79135 | FEN1-IN-7 | FLAP | |
FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells. Additionally, it targets the related endonuclease, xeroderma pigmento... | |||
T78192 | FEN1-IN-5 | FLAP | |
FEN1-IN-5 (compound 12A) is a potent Flap endonuclease-1 (FEN1) inhibitor with an IC50 value of 12 nM, playing a role in DNA repair mechanisms [1]. | |||
T79134 | FEN1-IN-6 | FLAP | |
FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and additionally targets the related endonuclease xeroderma pigmentosum G (XPG) wit... | |||
T68449 | JFD00950 | ||
JFD00950 is a human flap endonuclease 1 (FEN1) inhibitor with in vitro inhibition of flap cleavage activity as well as cytotoxic activity against a colon cancer cell line, DLD-1. |