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Search Results for " eltanexor "

2

Compounds

Cat No. Product Name Synonyms Targets
T11766L Eltanexor ONO-7706,KPT-8602,ATG-016 Others
Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes ...
T11766 Eltanexor Z-isomer KPT-8602 (Z-isomer) Others
Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively.Eltanexor Z-isomer is the less active isomer of KPT-8602. KPT-8602 is a...
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