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Search Results for " ezh2-in-2 "

8

Compounds

Cat No. Product Name Synonyms Targets
T9700 EZH2-IN-2 Histone Methyltransferase
EZH2-IN-2 is a EZH2 inhibitor with an IC50 of 64 nM.
T25400 EZH2-IN-3 EZH2 inhibitor 3,EZH2-inhibitor-3
EZH2-IN-3 is an inhibitor of EZH2 and EZH1 with selective impact on diffuse large B cell lymphoma cell growth.
T40310 PARP/EZH2-IN-1 PARP/EZH2-IN-1
PARP/EZH2-IN-1 is a novel compound that functions as a dual inhibitor for both PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 nM), showing promising potential for the treatment of triple-negative breast cancer with wild-type B...
T40323 EZH2-IN-6 EZH2-IN-6
EZH2-IN-6 is an EZH2 inhibitor with enhanced antitumor activity.
T38827 EZH2-IN-5 EZH2-IN-5
EZH2-IN-5 is a highly effective inhibitor of EZH2, displaying remarkable potency against both wild-type and mutant Tyr641 EZH2, with IC50 values of 1.52 nM and 4.07 nM, respectively.
T39497 EZH2-IN-4 EZH2-IN-4
EZH2-IN-4 is a highly potent EZH2 inhibitor that can be taken orally. It exhibits inhibitory effects against wild type (WT) 5-membered (5-mer) EZH2 and mutant 5-mer EZH2, with IC 50 values of 0.923 nM and 2.65 nM, respec...
T67883 EZH2-IN-15 SHR2554 Histone Methyltransferase
EZH2-IN-15 is a specific inhibitor of histone modifier enhancer of zeste 2 (EZH2). EZH2 is aberrantly overexpressed in a number of human cancers that controls the adaptive response via regulation of Treg activity. Intrat...
T74675 MS8815
MS8815, a selective proteolysis targeting chimera (PROTAC) degrader of enhancer of zeste homolog 2 (EZH2), exhibits inhibitory activity with an IC50 value of 8.6 nM. It is utilized in the research of triple-negative brea...
TargetMol