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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9700 | EZH2-IN-2 | Histone Methyltransferase | |
EZH2-IN-2 is a EZH2 inhibitor with an IC50 of 64 nM. | |||
T25400 | EZH2-IN-3 | EZH2 inhibitor 3,EZH2-inhibitor-3 | |
EZH2-IN-3 is an inhibitor of EZH2 and EZH1 with selective impact on diffuse large B cell lymphoma cell growth. | |||
T40310 | PARP/EZH2-IN-1 | PARP/EZH2-IN-1 | |
PARP/EZH2-IN-1 is a novel compound that functions as a dual inhibitor for both PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 nM), showing promising potential for the treatment of triple-negative breast cancer with wild-type B... | |||
T40323 | EZH2-IN-6 | EZH2-IN-6 | |
EZH2-IN-6 is an EZH2 inhibitor with enhanced antitumor activity. | |||
T38827 | EZH2-IN-5 | EZH2-IN-5 | |
EZH2-IN-5 is a highly effective inhibitor of EZH2, displaying remarkable potency against both wild-type and mutant Tyr641 EZH2, with IC50 values of 1.52 nM and 4.07 nM, respectively. | |||
T39497 | EZH2-IN-4 | EZH2-IN-4 | |
EZH2-IN-4 is a highly potent EZH2 inhibitor that can be taken orally. It exhibits inhibitory effects against wild type (WT) 5-membered (5-mer) EZH2 and mutant 5-mer EZH2, with IC 50 values of 0.923 nM and 2.65 nM, respec... | |||
T67883 | EZH2-IN-15 | SHR2554 | Histone Methyltransferase |
EZH2-IN-15 is a specific inhibitor of histone modifier enhancer of zeste 2 (EZH2). EZH2 is aberrantly overexpressed in a number of human cancers that controls the adaptive response via regulation of Treg activity. Intrat... | |||
T74675 | MS8815 | ||
MS8815, a selective proteolysis targeting chimera (PROTAC) degrader of enhancer of zeste homolog 2 (EZH2), exhibits inhibitory activity with an IC50 value of 8.6 nM. It is utilized in the research of triple-negative brea... |