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Cat No. | Product Name | Synonyms | Targets |
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T63970 | EZH2-IN-11 | ||
EZH2-IN-11 is a potent inhibitor of E2HZ. The oncogenic activity of EZH2 has been demonstrated in numerous studies in a variety of different cancer types and EZH2-IN-11 has shown research potential for cancer diseases. | |||
T17002 | Tazemetostat hydrobromide | E-7438 hydrobromide,EPZ-6438 hydrobromide | Histone Methyltransferase |
Tazemetostat hydrobromide (E-7438 hydrobromide) is a potent and selective EZH2 inhibitor. Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 (Ki: 2.5 n... | |||
T15240 | Tazemetostat trihydrochloride | EPZ-6438 trihydrochloride,E-7438 trihydrochloride | Histone Methyltransferase |
Tazemetostat trihydrochloride is a selective and orally available inhibitor of EZH2 (IC50: 4 nM for rat EZH2). It inhibits the activity of human PRC2-containing wild-type EZH2 (Ki: 2.5 nM). It inhibits EZH2 (IC50s: 11 an... |