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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39497 | EZH2-IN-4 | EZH2-IN-4 | |
EZH2-IN-4 is a highly potent EZH2 inhibitor that can be taken orally. It exhibits inhibitory effects against wild type (WT) 5-membered (5-mer) EZH2 and mutant 5-mer EZH2, with IC 50 values of 0.923 nM and 2.65 nM, respec... | |||
T17002 | Tazemetostat hydrobromide | E-7438 hydrobromide,EPZ-6438 hydrobromide | Histone Methyltransferase |
Tazemetostat hydrobromide (E-7438 hydrobromide) is a potent and selective EZH2 inhibitor. Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 (Ki: 2.5 n... | |||
T15240 | Tazemetostat trihydrochloride | EPZ-6438 trihydrochloride,E-7438 trihydrochloride | Histone Methyltransferase |
Tazemetostat trihydrochloride is a selective and orally available inhibitor of EZH2 (IC50: 4 nM for rat EZH2). It inhibits the activity of human PRC2-containing wild-type EZH2 (Ki: 2.5 nM). It inhibits EZH2 (IC50s: 11 an... |