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Search Results for " eif4f "

Targets

5

Compounds

7

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T5173 SBI-0640756 SBI 0640756,SBI-756 PERK , Autophagy
SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.
T27330 FL3
FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.
T73001 eIF4A3-IN-9
eIF4A3-IN-9, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 29, 450, and 80 nM for myc-LUC, tub-LUC, and growth inhibition in MBA-MB-231 cells, respectively. It i...
T72943 eIF4A3-IN-17
eIF4A3-IN-17, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 0.9, 15, and 1.8 nM for myc-LUC, tub-LUC, and growth inhibition of MBA-MB-231 cells, respectively. Th...
T72944 eIF4A3-IN-18
eIF4A3-IN-18, a silvestrol analogue, disrupts the formation of the eIF4F translation complex, exhibiting EC 50 values of 0.8, 35, and 2 nM for myc-LUC, tub-LUC, and the growth inhibition of MBA-MB-231 cells, respectively...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01307 EIF4A2 Protein, Human, Recombinant (GST) Human E. coli
EIF4A2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 73.4 kDa and the accession number is Q14240.
TMPJ-00507 EIF4E Protein, Human, Recombinant Human E. coli
Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and int...
TMPH-01312 EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc) Human E. coli
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-01313 EIF4G1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-01306 EIF4A1 Protein, Human, Recombinant (His & Myc) Human E. coli
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary str...
TMPJ-01109 EIF4EBP2 Protein, Human, Recombinant (His) Human E. coli
Eukaryotic Translation Initiation Factor 4E-Binding Protein 2 (EIF4EBP2) is a member of the Eukaryotic Translation Initiation Factor 4E Binding Protein Family. EIF4EBP2 regulates eIF4E activity by preventing its assembly...
TMPH-01282 ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in th...
TargetMol