egfr-in-18 — TargetMol Chemicals

Search Result

Search Results for " egfr-in-18 "

All TargetMol products are for research or drug registration purposes only and cannot be used for human consumption.
We do not provide products or services to individuals.
Please comply with the intended use and do not use TargetMol products for any other purpose in violation of laws and regulations.

Compounds

Cat No.	Product Name	Synonyms	Targets
T64170	EGFR-IN-18
	EGFR-IN-18 is a potent inhibitor of the enzymatic activity of the L858R/T790M/C797S mutant EGFR (4.9 nM) and is also able to reduce the enzymatic activity of wild-type EGFR (47 nM).
T11158	EGFR-IN-11		EGFR
	EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1.		EGFR
T60076	Oritinib	SH-1028	EGFR
	Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can ...		EGFR
T75165	HER2-IN-14
	HER2-IN-14 (Compound 34) is a potent inhibitor of HER2, achieving an inhibitory concentration (IC50) of 18 nM. Additionally, this compound exhibits inhibitory activity against wild-type EGFR (wt-EGFR) with an IC50 of 6.3...
T81596	Os30		EGFR
	Os30 is a potent fourth-generation EGFR inhibitor, specifically targeting the EGFRC797S-TK mutation with IC50 values of 18 nM for EGFRDel19/T790M/C797S TK and 113 nM for EGFRL858R/T790M/C797S TK. It effectively suppresse...		EGFR

Compounds