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Search Results for " dxd "

6

Compounds

Cat No. Product Name Synonyms Targets
T11249L Dxd Exatecan derivative for ADC,OQM5SD32BQ,UNII-OQM5SD32BQ Topoisomerase
Dxd (OQM5SD32BQ) is a potent inhibitor of DNA topoisomerase I with an IC50 of 0.31 μM. It is used as a conjugated drug of HER2-targeting ADC.
T36646 Trastuzumab deruxtecan DS-8201a,VRN-101099,DS 8201,T-DXd Others
Trastuzumab deruxtecan (T-DXd) is an antibody-activated molecule coupling (ADC) with anticancer and antitumour activity.Trastuzumab deruxtecan has been shown to have an ameliorative effect in HER2-positive breast and gas...
T77891 Propargyl-PEG4-GGFG-DXd
Propargyl-PEG4-GGFG-DXd is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising an ADC linker and the DNA topoisomerase I inhibitor known as DXd [1].
T39730 Datopotamab deruxtecan Dato-DXd,DS-1062 Others
Datopotamab deruxtecan (DS-1062; Dato-DXd) is an antibody-drug conjugate (ADC) that specifically targets trophoblast cell surface antigen 2 (TROP2). This compound exhibits high antitumor activity.
T77910 Patritumab deruxtecan U3-1287,HER3-DXd
Patritumab deruxtecan (HER3-DXd), an antibody-drug conjugate (ADC), comprises a fully human anti-HER3 IgG1 monoclonal antibody, Patritumab, linked to a topoisomerase I inhibitor payload through a tetrapeptide-based cleav...
T15098 Deruxtecan Others
Deruxtecan is an ADC drug-linker conjugate consisting of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker for the synthesis of DS-8201 and U3-1402.
TargetMol