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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15098 | Deruxtecan | Others | |
Deruxtecan is an ADC drug-linker conjugate consisting of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker for the synthesis of DS-8201 and U3-1402. | |||
T36646 | Trastuzumab deruxtecan | DS-8201a,VRN-101099,DS 8201,T-DXd | Others |
Trastuzumab deruxtecan (T-DXd) is an antibody-activated molecule coupling (ADC) with anticancer and antitumour activity.Trastuzumab deruxtecan has been shown to have an ameliorative effect in HER2-positive breast and gas... | |||
T39730 | Datopotamab deruxtecan | Dato-DXd,DS-1062 | Others |
Datopotamab deruxtecan (DS-1062; Dato-DXd) is an antibody-drug conjugate (ADC) that specifically targets trophoblast cell surface antigen 2 (TROP2). This compound exhibits high antitumor activity. | |||
T77910 | Patritumab deruxtecan | U3-1287,HER3-DXd | |
Patritumab deruxtecan (HER3-DXd), an antibody-drug conjugate (ADC), comprises a fully human anti-HER3 IgG1 monoclonal antibody, Patritumab, linked to a topoisomerase I inhibitor payload through a tetrapeptide-based cleav... | |||
T83576 | (1R)-Deruxtecan | ||
Deruxtecan (1R) is a drug-linker conjugate for antibody-drug conjugates (ADC) [1]. | |||
T77816 | Deruxtecan analog 2 | ||
Deruxtecan Analog 2 (example 9 P3), a Deruxtecan derivative, serves as an agent-linker conjugate integrating Camptothecin (CPT), a Topo I inhibitor active against colorectal, breast, lung, and ovarian cancers, with a dis... | |||
T9901A-007 | Datopotamab | Others | |
Datopotamab (CDP7657) is a TROP2-targeting antibody that is a naked antibody to Datopotamab deruxtecan and can be used to synthesize active antibody conjugators (Datopotamab deruxtecan). | |||
T77896 | Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | ||
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC linker utilized in the synthesis of drug-linker conjugates specific to ADCs, notably for creating Deruxtecan, a potent drug-linker conjugate [1]. |