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Search Results for " dabrafenib "

3

Compounds

Cat No. Product Name Synonyms Targets
T1903 Dabrafenib GSK2118436A,GSK2118436 Raf
Dabrafenib (GSK2118436A) is a Raf inhibitor that inhibits C-Raf and B-RafV600E (IC50=5/0.6 nM) and is ATP-competitive. Dabrafenib exhibits antitumor activity for the treatment of B-RafV600E-mutated melanoma.
T8474 Dabrafenib Mesylate GSK 2118436B,GSK2118436 Mesylate Raf
Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively).
T63210 Everafenib
Everafenib is a potent BRAF inhibitor that crosses the blood-brain barrier and also inhibits the MAPK pathway. Everafenib inhibits the activity of a range of V600EBRAF melanoma cell lines (IC50: 2-10 nM) and is more effe...
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