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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16024 | MC-GGFG-DX8951 | Others | |
MC-GGFG-DX8951 is a drug-linker conjugate designed for antibody-drug conjugation (ADC) that demonstrates antitumor activity through the deployment of DX8951, a DNA topoisomerase I inhibitor, connected using the protease-... | |||
T77847 | MC-Val-Cit-PAB-Exatecan | MC-Val-Cit-PAB-DX8951 | |
MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a conjugate of the DNA topoisomerase I inhibitor DX-8951 and a cathepsin-cleavable antibody-drug conjugate (ADC) linker, designed for targeted cancer therapy application... | |||
T75117 | Py-MAA-Val-Cit-PAB-DX8951 | ||
Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1]. | |||
T11249 | Exatecan | DX-8951,DX-8951f | Topoisomerase |
Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL).Exatecan has antitumor activity and may be used in cancer research. |