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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11655 | Indomethacin-D4 | Indometacin-D4 | CDK |
Indomethacin-D4 is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells. | |||
T19547 | Rebamipide-d4 | OPC12759 D4,Rebamipide D4,Proamipide D4 | Others |
Rebamipide D4 is deuterium labeled Rebamipide. | |||
T19602 | Vitamin D4 | Others | |
Vitamin D4 is the active Vitamin D analog. | |||
T11870 | Losartan D4 | DuP-753 D4 | Others |
Losartan D4, the deuterium-labeled version of Losartan, functions as an angiotensin II receptor antagonist. It inhibits the interaction between angiotensin II and AT1 receptors by competing for binding, achieving an IC50... | |||
T11536 | Haloperidol (D4') | Haloperidol D4' | Others |
Haloperidol D4' is deuterium-labeled haloperidol. Haloperidol is a dopamine D2 receptor antagonist. | |||
T11247 | Etravirine D4 | R-165335 D4,TMC-125 D4 | Others |
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine. | |||
T71981 | Gliclazide-d4 | ||
Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. ... | |||
T11675 | Irbesartan-d4 | SR-47436 D4,BMS-186295 D4 | Others |
Irbesartan D4, a deuterium-labeled variant of Irbesartan, is a highly potent and specific antagonist of the angiotensin II type 1 (AT1) receptor. | |||
T38042 | Resolvin D4 | Resolvin D4,RvD4 | |
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid . [1] It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreat... | |||
T12230 | Nitazoxanide-d4 | NTZ D4,NSC-697855 D4,Nitazoxanide D4 | Others |
Nitazoxanide D4 is the deuterium labeled Nitazoxanide. | |||
T13031 | Sulfamethoxazole-d4 | Ro 4-2130 D4 | Others |
Sulfamethoxazole D4 is a deuterium labeled Sulfamethoxazole (Ro 4-2130). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. | |||
T11934 | Macitentan-d4 | Macitentan D4,ACT-064992 D4 | Endothelin Receptor |
Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor).Macitentan-d4 is less toxic than Macitentan, has a longer... | |||
T11072 | Dofetilide D4 | UK 68789 D4 | Others |
Dofetilide D4 (UK 68789 D4), a deuterium-labeled version of Dofetilide, is categorized as a Class III antiarrhythmic medication. | |||
T11591 | Hydroxyzine D4 | Others | |
Hydroxyzine D4 is a deuterium-labeled variation of Hydroxyzine, a chemical compound known for its anticholinergic, anxiolytic, and analgesic properties. It is classified as a heterocyclic histamine H1-receptor antagonist... | |||
T11246 | Etoricoxib-d4 | MK-0663 D4,L-791456 D4,Etoricoxib D4 | Others |
Etoricoxib D4 is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.Etoricoxib D4 is a deuterium la... | |||
T10670 | Candesartan-d4 | CV-11974 D4 | Others |
Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor. | |||
T69395 | Nicotinamide-d4 | ||
Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized i... | |||
T19198 | Atovaquone-d4 | Others | |
Atovaquone D4 is the deuterium-labeled Atovaquone. Atovaquone is a medication used to treat or prevent pneumocystis babesia, malaria, toxoplasmosis, and pneumonia. | |||
T12300 | Olmesartan-d4 | RNH-6270 D4 | Others |
Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure. | |||
T11535 | Haloperidol D4 | Others | |
Haloperidol D4 is deuterium-labeled haloperidol. |