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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10108 | 3-Bromocytisine | (-)-3-Bromocytisine,(-)-9-Bromocytisine,3-Br-cytisine | AChR |
3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7). | |||
T0479 | Cytisinicline | Baptitoxine,Cytisine,Baphitoxine,Sophorine | AChR |
Cytisinicline (Sophorine), an alkaloid, is found naturally in several plants. | |||
T124561 | Cytisine Hydrochloride | ||
Cytisine Hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T124561. | |||
TN7054 | N-Formylcytisine | (-)-N-Formylcytisine | Others |
N-Formylcytisine ((-)-N-Formylcytisine) is a natural product isolated from the stem bark of Maackia amurensis. | |||
T5S0994 | N-Methylcytisine | Caulophylline | Others , AChR |
1. N-Methylcytisine (Caulophylline)'s nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentrat... | |||
TN6775 | Acetylcytisine | 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one,3-acetyl-1,2,3,4,5,6-hexahydro-, (1R)-,11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene | Others |
Acetylcytisine (11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene) is a natural product of The herbs of Genista tinctoria L. | |||
T16563L | Pozanicline hydrochloride | AChR | |
Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an α4β2-selective nAChR agonist... | |||
T29509 | A-366833 | A366833 | |
A-366833 is a novel nicotinic acetylcholine receptor (NACHR) ligand developed by Abbott that binds to the agonist binding site ([3H]-cytisine) with a Ki value of 3.1 nM and shows agonist selectivity for alpha4beta2 NACHR... | |||
T60474 | Tebanicline dihydrochloride | ||
Tebanicline dihydrochloride (Ebanicline dihydrochloride) is a nAChR modulator with effective orally analgesic activity. Tebanicline dihydrochloride inhibits the cytisine binding to α4β2 neuronal nAChRs with a Ki of 37 pM... | |||
T16563 | Pozanicline | ABT-089 | AChR |
Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine... | |||
T4246L | Varenicline | ||
Varenicline (CP 526555), a cytisine-based nicotinic ligand, is a potent partial agonist for the α4β2 nicotinic acetylcholine receptor (nAChR) with an EC50 value of 2.3 μM and acts as a full agonist for α7 and α3β4 nAChRs... | |||
T37202 | CC4 | CC4 | |
High affinity and subtype selective α6β2 and α4β2 partial agonist (Ki values are 12 and 26nM for rat α6β2 and α4β2 receptors respectively). Has low affinity for α3β4 and α7 receptors (Ki values are 4.8 and 13 μM for huma... |