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Search Results for " cytisine "

12

Compounds

Cat No. Product Name Synonyms Targets
T10108 3-Bromocytisine (-)-3-Bromocytisine,(-)-9-Bromocytisine,3-Br-cytisine AChR
3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).
T0479 Cytisinicline Baptitoxine,Cytisine,Baphitoxine,Sophorine AChR
Cytisinicline (Sophorine), an alkaloid, is found naturally in several plants.
T124561 Cytisine Hydrochloride
Cytisine Hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T124561.
TN7054 N-Formylcytisine (-)-N-Formylcytisine Others
N-Formylcytisine ((-)-N-Formylcytisine) is a natural product isolated from the stem bark of Maackia amurensis.
T5S0994 N-Methylcytisine Caulophylline Others , AChR
1. N-Methylcytisine (Caulophylline)'s nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentrat...
TN6775 Acetylcytisine 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one,3-acetyl-1,2,3,4,5,6-hexahydro-, (1R)-,11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene Others
Acetylcytisine (11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene) is a natural product of The herbs of Genista tinctoria L.
T16563L Pozanicline hydrochloride AChR
Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an α4β2-selective nAChR agonist...
T29509 A-366833 A366833
A-366833 is a novel nicotinic acetylcholine receptor (NACHR) ligand developed by Abbott that binds to the agonist binding site ([3H]-cytisine) with a Ki value of 3.1 nM and shows agonist selectivity for alpha4beta2 NACHR...
T60474 Tebanicline dihydrochloride
Tebanicline dihydrochloride (Ebanicline dihydrochloride) is a nAChR modulator with effective orally analgesic activity. Tebanicline dihydrochloride inhibits the cytisine binding to α4β2 neuronal nAChRs with a Ki of 37 pM...
T16563 Pozanicline ABT-089 AChR
Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine...
T4246L Varenicline
Varenicline (CP 526555), a cytisine-based nicotinic ligand, is a potent partial agonist for the α4β2 nicotinic acetylcholine receptor (nAChR) with an EC50 value of 2.3 μM and acts as a full agonist for α7 and α3β4 nAChRs...
T37202 CC4 CC4
High affinity and subtype selective α6β2 and α4β2 partial agonist (Ki values are 12 and 26nM for rat α6β2 and α4β2 receptors respectively). Has low affinity for α3β4 and α7 receptors (Ki values are 4.8 and 13 μM for huma...
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