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Search Results for " cypa "

6

Compounds

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T64779 Cypate
3-(2-(7-(3-(2-Carboxyethyl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-2-yl)hepta-2,4,6-trien-1-ylidene)-1,1-dimethyl-1,2-dihydro-3H-benzo[e]indol-3-yl)propanoate is a useful organic compound for research related to life scienc...
T64220 Cyclophilin inhibitor 3
Cyclophilin inhibitor 3 (compound 7c), a potent inhibitor of cyclophilin A (CypA), exhibited potent anti-HCV effects with an EC50 value of 4.2 μM.
T79870 RMC-4998 Ras
RMC-4998 is a molecular glue compound exhibiting potent antitumor activity, capable of forming a ternary complex with CYPA and an activated KRAS G12C mutation. Binding of CYPA to KRAS G12C impedes the interaction between...
T36642 RAS/RAS-RAF-IN-1
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1]. RAS/RAS-RAF-IN-1 (compound 89; for ...
T75131 RMC-6291
RMC-6291 is an orally active and covalent inhibitor of KRAS G12C (ON) . RMC-6291 forms a tri-complex within tumor cells between KRAS G12C (ON) and cyclophilin A (CypA). Thus, RMC-6291 prevents KRAS G12C (ON) from signali...
T10919 Cyclophilin inhibitor 1 Others
Cyclophilin inhibitor 1 is an effective and orally bioavailable cyclophilin A inhibitor with a Kd of 5 nM, showing potent anti-HCV activity, and an EC50 for HCV 2a of 98 nM.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00048 CYPA Protein, Mouse, Recombinant Mouse E. coli
Peptidyl-prolyl cis-trans isomerase A is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins(CyPs) are a family of proteins found in organisms ranging from prokary...
TMPJ-01049 CYPA Protein, Human, Recombinant Human E. coli
Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biolo...
TMPY-02177 Cyclophilin A Protein, Human, Recombinant (His) Human E. coli
Cyclophilin A Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.4 kDa and the accession number is P62937.
TMPY-01593 Cyclophilin A Protein, Mouse, Recombinant (His) Mouse E. coli
Cyclophilin A Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.8 kDa and the accession number is P17742.
TMPH-00817 Pectate lyase 1 Protein, Hesperocyparis arizonica, Recombinant (His & Myc) Hesperocyparis arizonica E. coli
Has pectate lyase activity. Pectate lyase 1 Protein, Hesperocyparis arizonica, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 42.6 kDa and...
TMPH-00364 Pectate lyase 1 Protein, Chamaecyparis obtusa, Recombinant (His & SUMO) Chamaecyparis obtusa E. coli
Has pectate lyase activity. Pectate lyase 1 Protein, Chamaecyparis obtusa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.1 kDa and the acce...
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