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Search Results for " chk1-in-3 "

3

Compounds

Cat No. Product Name Synonyms Targets
T10791 CHK1-IN-3 Chk
CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).
T68981 PD-321852
PD-321852 is a small-molecule Chk1 inhibitor, which potentiates gemcitabine-induced clonogenic death in a panel of pancreatic cancer cell lines and evaluated the relationship between endpoints associated with Chk1 inhibi...
T36704 CCT241533 dihydrochloride CCT 241533 dihydrochloride
Potent Chk2 inhibitor (IC50 = 3 nM). Shows >63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide-induced DNA damage in HT29 cells. Blocks ionizing radi...
TargetMol