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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10739 | CDK8/19-IN-1 | CDK | |
CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9). | |||
T81137 | SNX7886 | PROTACs | |
SNX7886 is a potent PROTAC (proteolysis-targeting chimera) that effectively degrades CDK8 and CDK19, achieving 90% degradation of CDK8 and 80% degradation of CDK19 in 293 cells [1]. |