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Search Results for " cdk1-in-5 "

5

Compounds

Cat No. Product Name Synonyms Targets
T63437 CDK1-IN-5
CDK1-IN-5 (10h) is a selective CDK1 inhibitor that acts on CDK1 (IC50: 42.19 nM), CDK2 (IC50: 188.71 nM) and CDK5 (IC50: 354.15 nM). CDK1-IN-5 affects the cell cycle and inhibits cancer cell growth and can be used in can...
T61254 CDK1/Cyc B-IN-1
CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer ...
T16784 Roniciclib BAY 1000394 CDK
Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) v...
T69200 CGP74514A
CGP74514A is a CDK1 inhibitor with potential anticancer activity. In U937 cells, CGP74514A - induced apoptosis (5 microM) became apparent within 4 hr and approached 100% by 24 hr. The pan- caspase inhibitor Boc-fmk and t...
T83936 LL-K9-3
LL-K9-3, a selective hydrophobic tagging technology (HyT)-based degrader, specifically targets the CDK9-cyclin T1 complex, displaying DC50 values of 589 nM for cyclin T1 and 662 nM for CDK9. This compound consists of the...
TargetMol