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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10156 | CCR3 antagonist 1 | CCR | |
CCR3 antagonist 1 is a potent CCR3 antagonist, used for the research of inflammatory and immunologic diseases. | |||
T11699 | J-113863 | CCR | |
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor... | |||
T4674 | SB297006 | SB 297006 | CCR |
SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ... | |||
T23321 | SB 328437 | (S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate,ZINC29222893 | CCR |
SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM). | |||
T11521 | GW 766994 | GW 994 | CCR |
GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment. | |||
T30535 | BMS-639623 | UNII-PON9OFP69G,PON9OFP69G,BMS 639623,CHEMBL399495 | |
BMS-639623 is a CCR3 antagonist with a picomolar inhibitory effect on eosinophilic chemotaxis and can be used in the treatment of asthma. | |||
T36620 | ALK4290 | ALK4290 | |
ALK4290 (AKST4290) is a potent and orally actively CCR3 inhibitor, compound Example 2, with a Ki of 3.2 nM for hCCR3[1]. ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsoni... | |||
T23492 | UCB 35625 | Others | |
chemokine CCR1 and CCR3 receptor antagonist | |||
T30865 | CH-0076989 | UNII-9E629B19WL,CHEMBL485834,9E629B19WL,CH 0076989 | |
CH-0076989 is a chemokine receptor CCR3 agonist. | |||
T75499 | Maceneolignan H | ||
Maceneolignan H (Compound 8), a neolignane derived from the arils of Myristica fragrans, acts as a selective CCR3 antagonist with an EC 50 value of 1.4 μM. This compound shows promise for allergic disease research [1]. | |||
T76504 | CKLF1-C19 | ||
CKLF1-C19, the C-terminal peptide of human chemokine-like factor 1 (CKLF1), interacts with CCR4 and inhibits chemotaxis induced by CKLF1 and CCL17. It also suppresses allergic lung inflammation by inhibiting chemotaxis m... |