Powder: -20°C for 3 years
In solvent: -80°C for 2 years
GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.
Description | GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment. |
Targets&IC50 | CCR3:7.86 (pki) |
In vitro | GW 766994 (10 μM) reverses CCL11-induced activation of CDK5, phosphorylations of CDK5, GSK3β, and increased phosphorylation of tau in hippocampal neurons.GW 766994 is a specific chemokine receptor-3 (CCR3) antagonist, which has entered clinical trial for asthma and eosinophilic bronchitis. |
Synonyms | GW 994 |
Molecular Weight | 451.35 |
Formula | C21H24Cl2N4O3 |
CAS No. | 408303-43-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 56 mg/mL (124.07 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GW 766994 408303-43-5 Immunology/Inflammation Microbiology/Virology CCR GW 994 Inhibitor inhibitor inhibit