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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60930 | CAXII-IN-1 | ||
CAXII-IN-1 (Compound 17) has antitumor activity that is a selective inhibitor of CA XII. The Ki values of CAXII-IN-1 for hCA XII and hCA IX is 3.8 nM and 56.0 nM, respectively [1]. | |||
T2017 | U-104 | NSC-213841,MST-104 | Carbonic Anhydrase |
U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM). | |||
T61769 | HCAXII-IN-5 | ||
hCAXII-IN-5 (compound 6o) is a highly effective and specific inhibitor of hCAXII. The compound exhibits impressive binding affinities, with Ki values of >10000, >10000, 286.1, and 1.0 nM for hCAI, hCAII, hCAIX, and hCAXI... | |||
T63973 | HCAXII-IN-3 | ||
hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM). | |||
T61219 | HCAXII-IN-1 | ||
hCAXII-IN-1 demonstrates selective inhibition of tumor-related subtypes HCA IX and XII, making it potential leading molecules in the development of novel cancer therapeutic drugs with new mechanisms of action. | |||
T79411 | HCAXII-IN-7 | Carbonic Anhydrase | |
hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability. Moreover, it promotes apoptosis in 786-0, SF-539, and HS 578 T cell line... | |||
T62101 | HCAXII-IN-2 | ||
hCAXII-IN-2 (compound 5i) is a potent inhibitor of human carbonic anhydrase XII (hCA XII) (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity against hCA I and hCA II. | |||
T63276 | HCAXII-IN-4 | ||
hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII. | |||
T61873 | HCAIX/XII-IN-1 | ||
hCAIX/XII-IN-1, a potent inhibitor of both CAIX and CAXII, exhibits KI values of 0.48 μM for CAIX and 0.83 μM for CAXII, respectively. This compound demonstrates antiproliferative activity in vitro and induces apoptosis ... | |||
T61384 | HCAIX/XII-IN-4 | ||
hCAIX/XII-IN-4 (compound 6c) is a highly potent inhibitor of CAIX/XII. It exhibits Ki values of 4.5 nM, 23.6 nM, >10000 nM, and >10000 nM for CAXII, CAIX, CAI, and CAⅡ, respectively [1]. | |||
T36059 | Dichlorphenamide-13C6 | Dichlorphenamide-13C6 | |
Dichlorphenamide-13C6is intended for use as an internal standard for the quantification of dichlorphenamide by GC- or LC-MS. Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor ... |