6
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9915 | Eculizumab | Complement System | |
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5 | |||
T64611 | Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R | ||
Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R is a useful organic compound for research related to life sciences and the catalog number is T64611. | |||
T74551 | Avacincaptad pegol sodium | ||
Avacincaptad pegol (ARC1905), an anti-C5 RNA aptamer, prevents the cleavage of complement factor 5 (C5) into fragments C5a and C5b. It is currently under investigation for the treatment of age-related macular degeneratio... | |||
T74552 | Non-PEGylated/naked ARC1905 | ||
ARC1905, a non-PEGylated/naked anti-C5 RNA aptamer, functions by inhibiting the cleavage of complement factor 5 (C5) into its components, C5a and C5b, without PEG conjugation. This compound is currently being researched ... | |||
T31877 | Freselestat | ONO-PO 736,ONO-6818,ONO 6818,ONO6818 | |
Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9. Freselestat reduces inflammatory mediators during simulated cardiopulmonary bypass. | |||
T77190 | Crovalimab | ||
Crovalimab (SKY59; RO7112689) is a novel humanized antibody designed to target C5 in a pH-dependent manner, demonstrating binding affinities (KD) of 15.2 nM and 16.8 μM at pH levels of 7.4 and 5.8, respectively. Addition... |