c1r — TargetMol Chemicals

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Search Results for " c1r "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Targets
T78105	PAC1R antagonist 1	PACAP
	PAC1R antagonist 1 is an orally active PAC1 receptor antagonist that inhibits abnormal pain induced by pituitary adenylate cyclase-activating polypeptide (PACAP) and nerve damage, and may be used in the study of neoplasm...	PACAP
T76670	HMC1R agonist 1
	hMC1R agonist 1, with an EC 50 of 3 nM, exhibits at least 300-fold higher selectivity for hMC1R compared to hMC3R (EC 50 >902 nM), hMC4R (EC 50 >915 nM), and hMC5R (EC 50 >1000 nM). This compound demonstrates potential f...

Compounds

Recombinant Proteins

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Expression System：

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Cat No.	Product Name	Species	Expression System
TMPH-02601	C1RL Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum. C1RL Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.5 ...
TMPH-02602	C1RA Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
TMPH-02603	C1SB Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
TMPH-02596	C1QA Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and effi...
TMPH-02597	C1QA Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and effi...
TMPY-06585	C1s Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex comp...
TMPJ-00980	Complement Factor MASP3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of micro...
TMPY-01712	C1QB Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulon...
TMPJ-01064	Serpin G1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement sy...
TMPY-01692	NETO1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDAR...