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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6119 | Sotuletinib | BLZ945 | c-Fms , CSF-1R |
Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor (IC50: 1 nM), >1000-fold selective against its closest receptor tyrosine kinase homologs. | |||
T78603 | Sotuletinib dihydrochloride | BLZ945 dihydrochloride | c-Fms |
Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM. It promotes apoptosis in tumor cells and significantly restricts... |