Home Tools
Log in
Cart

Search Result

Search Results for " aβ42-in-2 "

8

Compounds

Cat No. Product Name Synonyms Targets
T9641 Aβ42-IN-2 Gamma-secretase
Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].
T4S0350 Licochalcone B Beta Amyloid , Others
1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...
T83407 2',3'-Dihydroxy-4',6'-dimethoxychalcone
2',3'-Dihydroxy-4',6'-dimethoxychalcone (compound 1) possesses the capacity to inhibit Amyloid β-protein (Aβ42) fibrillization and aggregation, demonstrating oral activity with detectable presence in the brain [1].
T37367 Amyloid-β (1-42) Peptide (trifluoroacetate salt)
Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-amino acid protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's disease.1,2,3Aggregation of Aβ42 results in the formation of ne...
T63216 γ-Secretase modulator 11
5-{8-[(3,4'-Difluoro[1,1'-biphenyl]-4-yl)methoxy]-2-methylimidazo[1,2-a]pyridin-3-yl}-N-methylpyridine-2-carboxamide (1o) exhibited high in vitro potency and brain exposure, was able to cause a significant reduction in b...
T76425 (Glu20)-Amyloid β-Protein (1-42)
(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly. This is attributed to the Glu20 mutation, which diminishes Aβ42's tendency to aggregate and inhibits the accum...
T36639 Donecopride (fumarate hydrate)
Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= ...
T37369 Amyloid-β (1-8, A2V) Peptide Amyloid-β (1-8, A2V) Peptide
Amyloid-β (1-8, A2V) is a truncated form of amyloid-β (Aβ) that contains a valine to alanine substitution at position 2 of the Aβ numbering convention (Aβ A2V), which corresponds to position 673 of the amyloid precursor ...
TargetMol