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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0238 | Lanabecestat | LY3314814,AZD3293 | BACE |
Lanabecestat (AZD3293) is a highly potent and highly permeable, orally active BACE1 inhibitor (Ki: 0.4 nM) that crosses the blood-brain barrier, Lanabecestat can be used for the study of neurological diseases like Alzhei... | |||
T10014 | (1α,1'S,4β)-Lanabecestat | (1α,1'S,4β)-AZD3293 | Others |
(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively. | |||
T70805 | Diethylnorspermine HBr | ||
Diethylnorspermine, also known as DENSPM, BE-333, DE-333 and N(1),N(11)-Diethylnorspermine, is a highly potent known inducer of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT). A designed... | |||
T70807 | Lanabecestat HCl | ||
Lanabecestat, also known as AZD3293 and LY3314814, is a potent, highly permeable, orally active, blood-brain barrier (BBB) penetrating, BACE1 inhibitor with unique slow off-rate kinetics. AZD3293 displayed significant do... |