3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3978 | Linerixibat | GSK2330672,Iinerixibat | HBV |
Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties. | |||
T28700 | SC-435 mesylate | SC-435,SC435,SC 435 | |
SC-435 is an ileal apical sodium co-dependent bile acid transporter (ASBT). SC-435 inhibits plasma cholesterol. | |||
T70688 | S 0960 | ||
S 0960 is a dimeric bile acid analogue that acts as a specific inhibitor of the apical sodium-dependent bile salt transporter (ASBT) in the ileum. |