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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6117 | Tivantinib | ARQ 197 | Apoptosis , c-Met/HGFR |
Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity. | |||
T83557 | (3S,4S)-Tivantinib | ARQ 198,(3S,4S)-ARQ 197 | |
(3S,4S)-Tivantinib, a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET, targets GSK3α and GSK3β—two novel enzymes implicated in the pathogenesis of non-small cell lung cancer (NSCLC) [1]. | |||
T83524 | (rel)-Tivantinib | (rel)-(3R,4R)-ARQ 198,(rel)-ARQ 197 | |
(rel)-Tivantinib is a potent, highly selective inhibitor of the receptor tyrosine kinase c-MET and has additional novel targets, GSK3α and GSK3β, that are critical in the cellular mechanisms of non-small cell lung cancer... |