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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14285 | AN11251 | Others | |
AN11251, a potent oral-active anti-Wolbachia agent, shows promise for treating onchocerciasis and lymphatic filariasis. Demonstrating EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines, it exhibits si... | |||
T12924 | Sitaxsentan | TBC-11251,IPI 1040 | Endothelin Receptor |
Sitaxsentan (TBC-11251) is A selective endothelin A (ETA) receptor antagonist. Endothelin is an effective vasoconstrictor. Sitaxsentan blocks the binding of endothelin to its receptors, thereby eliminating the harmful ef... |