2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38562 | AKN-028 | FLT | |
AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation. | |||
T29802 | AKN-028 trifluoroacetate | ||
AKN-028 trifluoroacetate induces cell cycle arrest, downregulation of Myc associated genes, and dose-dependent reduction of tyrosine kinase activity in acute myeloid leukemia. |