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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2053 | ADX-47273 | BA 94673139 | GluR |
ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM). | |||
T13441 | (R)-ADX-47273 | GluR | |
(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ). | |||
TQ0094 | JNJ-40411813 | ADX-71149 | GluR |
JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM). | |||
T16732 | Reproxalap | NS-2,ADX-102 | Others |
Reproxalap (NS-2) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. Reproxalap is a reactive aldehyde species sequestering agent for the treatment of the dry eye. | |||
T26568 | ADX-10061 | CEE-310,NNC-687,NNC-01-0687,CEE-03-310 | |
ADX-10061 is a dopamine D1 receptor antagonist. | |||
T4500 | ADX88178 | GluR | |
ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4. | |||
T26569 | ADX71441 | ADX 71441,ADX-71441 | |
ADX71441 is a GABAB positive allosteric modulator (PAM). ADX71441 increases urinary latencies and reduces the number of urinary events and the total and average urinary volumes. ADX71441 may also mitigate alcoholism and ... | |||
T82899 | Bempikibart | ADX-914 | |
Bempikibart (ADX-914), a human anti-IL-7Rα antibody, has potential applications in anti-inflammatory research [1]. | |||
T26570 | ADX71743 | ||
ADX71743 is a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7. | |||
T15134 | Dipraglurant | ADX48621 | Others |
Dipraglurant is a negative allosteric regulator (NAM) of blood-brain barrier transmissible mGluR5 with effective, selective and oral activity, with an IC50 value of 21 nM. Dipraglurant can treat levodopa-induced dyskines... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00220 | Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His) | Bovine | E. coli |
Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 th... |