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Search Results for " actriib "

3

Compounds

17

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T76993 Stamulumab
Stamulumab (MYO-029), a recombinant human IgG1λ antibody, targets and neutralizes myostatin by inhibiting its interaction with the ActRIIB receptor, leading to muscle fiber hypertrophy rather than hyperplasia in SCID mic...
T76860 Bimagrumab
Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody targeting the activin type II receptor (ActRII), exhibiting binding affinities (K D) of 1.7 pM for ActRIIB and 434 pM for ActRIIA, respectively. ...
T77076 Luspatercept
Luspatercept (ACE-536), a recombinant modified ActRIIB fusion protein, selectively binds to transforming growth factor β superfamily ligands, thereby enhancing erythrocyte production and advancing the maturation of eryth...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His) Mouse HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-00654 ACVR2B Protein, Human, Recombinant (hFc) Human HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-01022 ACVR2B Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-01051 ACVR2B Protein, Human, Recombinant (His) Human HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-04774 ALK-2/ACVR1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPJ-00314 ACVR2B Protein, Human, Recombinant (hFc & His) Human Human Cells
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors...
TMPY-03300 ALK-4/ACVR1B Protein, Rat, Recombinant (hFc) Rat HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-03100 ALK-4/ACVR1B Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-05483 ALK-4/ACVR1B Protein, Human, Recombinant (hFc) Human HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-01293 ALK-4/ACVR1B Protein, Human, Recombinant (His) Human HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-00444 ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc) Mouse HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-01096 ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03706 ALK-2/ACVR1 Protein, Canine, Recombinant (hFc) Canine HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03157 ALK-2/ACVR1 Protein, Rat, Recombinant (hFc) Rat HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-00658 ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc) Human HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03707 ALK-2/ACVR1 Protein, Canine, Recombinant (His) Canine HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03247 ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
ACVR2B Protein, Mouse, Recombinant (His)
TMPY-01281
Species: Mouse
Expression System: HEK293
ACVR2B Protein, Human, Recombinant (hFc)
TMPY-00654
Species: Human
Expression System: HEK293
ACVR2B Protein, Mouse, Recombinant (His & hFc)
TMPY-01022
Species: Mouse
Expression System: HEK293
ACVR2B Protein, Human, Recombinant (His)
TMPY-01051
Species: Human
Expression System: HEK293
ALK-2/ACVR1 Protein, Human, Recombinant (His)
TMPY-04774
Species: Human
Expression System: Baculovirus-Insect Cells
ACVR2B Protein, Human, Recombinant (hFc & His)
TMPJ-00314
Species: Human
Expression System: Human Cells
ALK-4/ACVR1B Protein, Rat, Recombinant (hFc)
TMPY-03300
Species: Rat
Expression System: HEK293
ALK-4/ACVR1B Protein, Rhesus, Recombinant (hFc)
TMPY-03100
Species: Rhesus
Expression System: HEK293
ALK-4/ACVR1B Protein, Human, Recombinant (hFc)
TMPY-05483
Species: Human
Expression System: HEK293
ALK-4/ACVR1B Protein, Human, Recombinant (His)
TMPY-01293
Species: Human
Expression System: HEK293
ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc)
TMPY-00444
Species: Mouse
Expression System: HEK293
ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc)
TMPY-01096
Species: Mouse
Expression System: HEK293
ALK-2/ACVR1 Protein, Canine, Recombinant (hFc)
TMPY-03706
Species: Canine
Expression System: HEK293
ALK-2/ACVR1 Protein, Rat, Recombinant (hFc)
TMPY-03157
Species: Rat
Expression System: HEK293
ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
TMPY-00658
Species: Human
Expression System: HEK293
ALK-2/ACVR1 Protein, Canine, Recombinant (His)
TMPY-03707
Species: Canine
Expression System: HEK293
ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc)
TMPY-03247
Species: Cynomolgus
Expression System: HEK293
TargetMol