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Cat No. | Product Name | Synonyms | Targets |
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T76993 | Stamulumab | ||
Stamulumab (MYO-029), a recombinant human IgG1λ antibody, targets and neutralizes myostatin by inhibiting its interaction with the ActRIIB receptor, leading to muscle fiber hypertrophy rather than hyperplasia in SCID mic... | |||
T76860 | Bimagrumab | ||
Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody targeting the activin type II receptor (ActRII), exhibiting binding affinities (K D) of 1.7 pM for ActRIIB and 434 pM for ActRIIA, respectively. ... | |||
T77076 | Luspatercept | ||
Luspatercept (ACE-536), a recombinant modified ActRIIB fusion protein, selectively binds to transforming growth factor β superfamily ligands, thereby enhancing erythrocyte production and advancing the maturation of eryth... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01281 | ACVR2B Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ... | |||
TMPY-00654 | ACVR2B Protein, Human, Recombinant (hFc) | Human | HEK293 |
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ... | |||
TMPY-01022 | ACVR2B Protein, Mouse, Recombinant (His & hFc) | Mouse | HEK293 |
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ... | |||
TMPY-01051 | ACVR2B Protein, Human, Recombinant (His) | Human | HEK293 |
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ... | |||
TMPY-04774 | ALK-2/ACVR1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been... | |||
TMPJ-00314 | ACVR2B Protein, Human, Recombinant (hFc & His) | Human | Human Cells |
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors... | |||
TMPY-03300 | ALK-4/ACVR1B Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer... | |||
TMPY-03100 | ALK-4/ACVR1B Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer... | |||
TMPY-05483 | ALK-4/ACVR1B Protein, Human, Recombinant (hFc) | Human | HEK293 |
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer... | |||
TMPY-01293 | ALK-4/ACVR1B Protein, Human, Recombinant (His) | Human | HEK293 |
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer... | |||
TMPY-00444 | ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer... | |||
TMPY-01096 | ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc) | Mouse | HEK293 |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been... | |||
TMPY-03706 | ALK-2/ACVR1 Protein, Canine, Recombinant (hFc) | Canine | HEK293 |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been... | |||
TMPY-03157 | ALK-2/ACVR1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been... | |||
TMPY-00658 | ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been... | |||
TMPY-03707 | ALK-2/ACVR1 Protein, Canine, Recombinant (His) | Canine | HEK293 |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been... | |||
TMPY-03247 | ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been... |