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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2105 | Veliparib dihydrochloride | ABT-888 dihydrochloride | PARP , Autophagy |
Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. | |||
T2591 | Veliparib | ABT-888,NSC 737664 | PARP , Autophagy |
Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy. | |||
T72862 | PARP-2/1-IN-2 | ||
PARP-2/1-IN-2, an enantiomer of Veliparib, serves as a potent inhibitor of PARP, demonstrating inhibition constants (Kis) of 2 nM for PARP-2 and 5 nM for PARP-1. This compound exhibits a half-maximal effective concentrat... |