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Search Results for " abt-199 "

3

Compounds

Cat No. Product Name Synonyms Targets
T2119 Venetoclax GDC-0199,ABT 199,ABT-199,ABT199 BCL , Autophagy
Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and orally active properties. Venetoclax has a 3-order-of-magnitude lower affinity for Bcl-xL and Bcl-W (Kis=48/245 nM). Venetoclax induces a...
T74015 Venetoclax N-oxide
Venetoclax N-oxide is an impurity of Venetoclax. Venetoclax (ABT-199; GDC-0199), a highly potent, selective, and orally bioavailable inhibitor of Bcl-2, demonstrates a Ki value of less than 0.01 nM [1].
T79242 Mcl-1 inhibitor 16
Mcl-1 Inhibitor 16 (Compound 9), a platinum-based mitochondrial-targeting agent, inhibits Mcl-1 and induces Bax/Bak-dependent apoptosis in cancer cells. This compound exhibits antitumor activity and may be utilized as a ...
TargetMol