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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T68408 | AMG-1 | ||
AMG-1 is a specific CRAC channel inhibitor. AMG-1 blocks the function of effector T cells, but not regulatory T cells in vitro and it attenuates the progression and severity of EAE in vivo. | |||
T8409 | SYN1143 | RON-IN-1,AMG-1 | c-Met/HGFR |
SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively. |