2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15546 | ICA | N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine | Potassium Channel , Parasite |
ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM). | |||
T9009 | ICA-105574 | ICA,3-nitro-N-[4-phenoxyphenyl]-benzamide | HER |
ICA-105574 (ICA) is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel. |