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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T69842 | DB2313 HCl | ||
DB2313 is a first-in-class potent small-molecule inhibitor of PU.1. DB2313 disrupts the interaction of PU.1 with target gene promoters and leads to down-regulation of canonical PU.1 transcriptional targets. | |||
T9707 | DB2313 | Carboximidamide | Apoptosis |
DB2313 (Carboximidamide) is a potent transcription factor PU.1 inhibitor, IC50=14 nM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis of acute myeloid leukemia (AML) cells, an... |