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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10065L | 2',3'-cGAMP sodium | 2'-3'-cyclic GMP-AMP sodium | STING , cGAS |
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium), a cGAMP synthase (cGAS) affecting cytoplasmic DNA production as a second messenger, is a transmembrane bridging protein that is a key component of the cellular innate imm... | |||
T40224 | 2',3'-cGAMP-C2-PPA | 2',3'-cGAMP-C2-PPA | |
2',3'-cGAMP-C2-PPA (45) is a cyclic di-nucleotide that acts as a STING agonist (US20210015941A1). It is a drug-linker conjugate for antibody-drug conjugates (ADC) used in the targeted treatment of cancer. | |||
T39582 | 2',3'-cGAMP-C2-SH | 2',3'-cGAMP-C2-SH | |
2', 3'-cGAMP-C2-SH is a ADC cytotoxin. | |||
T10065 | 2',3'-cGAMP | 2'-3'-cyclic GMP-AMP | STING , cGAS |
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP binds to STING to form a dimer, inducing the produc... | |||
T73717 | cGAMP diammonium | ||
cGAMP (Cyclic GMP-AMPP) diammonium serves as an intrinsic second messenger in metazoans, initiating the production of interferons upon cytosolic DNA detection. It activates the stimulator of interferon genes (STING), sub... | |||
T38319 | 93-O17O | 93-O17O | |
93-O17O is a chalcogen-containing cationic lipidoid.1,2It has been used in the generation of lipid nanoparticles (LPNs). LPNs containing 93-O17O localize to the spleen after intravenous injection into mice.1LPNs containi... |