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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T78582 | 15-keto-Prostaglandin E2 | 15-keto-PGE2 | Prostaglandin Receptor |
15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast cancer cell growth and progression. Additionally, it binds and stabilizes the EP2 and EP4 recep... | |||
T8763 | PTGR2-IN-1 | PTGR2-IN-22 | Others |
PTGR2-IN-1 is a potent inhibito of PTGR2r(IC50 : 0.7 μM). It increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells. | |||
T67766 | HHS-0701 | Others | |
HHS-0701 is a sulfur-triazole exchange (SuTEx) ligand. HHS-0701 is a potent inhibitor of tyrosine-reactive prostaglandin reductase 2 (PTGR2). HHS-0701 can block PTGR2 metabolism of the lipid substrate 15-Keto-PGE2. | |||
T36167 | 8-iso-15-keto Prostaglandin F2β | 8-iso-15-keto Prostaglandin F2β | |
8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin. It is one of 64 possible isomers of PGF2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2β exhibits ... |