11c — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6042	[11C]MP 10	Mardepodect,PF-2545920	PDE
	[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.		PDE
T29476	6-OH-BTA-0	Pittsburgh Compound-B precursor,11C-PiB Precursor
	6-OH-BTA-0 is the precursor for preparing 11C-PiB, which is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.
T41078	Lipopolysaccharides, Escherichiacoli	Lipopolysaccharide, E. coli O111:B4	Others
	Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) is a macromolecular component of the outer membrane of Gram-negative bacteria, consisting of three regions: lipid A, oligosaccharide core and O-specific polysacchari...		Others
T21000	PiB	Pittsburgh Compound-B,6-OH-BTA-1	Others
	PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.		Others
T29258	(R)-N-Desmethyl PK11195	(R)-N-Desmethyl PK 11195,(R)-N-Desmethyl PK-11195,(R)-N Desmethyl PK11195,(R) N-Desmethyl PK11195
	(R)-N-Desmethyl PK11195 is a precursor for (R)-[N-Methyl-11C-]PK11195.
T32904	LSN3172176 Precursor	LSN-3172176 Precursor,LSN 3172176 Precursor
	LSN3172176 Precursor is a precursor for 11C-radiolabelling LSN3172176 PET scan.
T79262	SSI-4		Stearoyl-CoA Desaturase (SCD)
	SSI-4 is a Stearoyl CoA desaturase 1 (SCD1) inhibitor that can be labeled with carbon-11 (11C) for use as a ligand in small animal in vivo PET/CT imaging studies of SCD1 [1].		Stearoyl-CoA Desaturase (SCD)
T31389	Desmethyl-HD-800	Desmethyl-HD800,Desmethyl HD800
	Desmethyl-HD-800 is a PET precursor of preparing radiolabel [11C]HD-800, a high affinity brain penetrant PET tracer for imaging microtubules.
T81617	OfHex1-IN-1
	OfHex1-IN-1 (compound 11c), a β-N-acetylhexosaminidase from Ostrinia furnacalis inhibitor, exhibits high potency and selectivity with an IC50 of 28.1 μM and a K i of 25.6 μM. It is applicable in research for developing g...
T36744	CDK9 Antagonist-1	CDK9 Antagonist-1
	CDK9 Antagonist-1 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form...
T17728	PROTAC CDK9 degrader-2		Others
	PROTAC CDK9 degrader-2 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to...		Others
T78753	Aurora Kinases-IN-4		Aurora Kinase
	Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM. It demonstrates cell proliferation inhibition in SJSA-1, MDA-MB-231, A549, and HeLa cell lines ...		Aurora Kinase