Markers of T cell activation include CD69, CD71 and CD25 (also a marker for Treg cells), and HLA-DR (a marker of human T cell activation). CTLA-4 expression is also up-regulated on activated T cells, which in turn outcompetes CD28 for binding to the B7 proteins. This is a checkpoint mechanism to prevent over activation of the T cell.
In dendritic cells, the most important CD markers of activation are CD80, CD86 and CD83. CD40 is already expressed in most immature dendritic cells, although their expression intensity increases strongly, following the activation.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00075 | CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
|
Mouse | Human Cells |
CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular ... | |||
TMPJ-00129 | BTLA Protein, Human, Recombinant (His)
BTLA Protein, Human, Recombinant (His)
|
Human | Human Cells |
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induc... | |||
TMPJ-01070 | CD83 Protein, Human, Recombinant (hFc)
CD83 Protein, Human, Recombinant (hFc)
|
Human | Human Cells |
CD83 antigen is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD83 is expressed by activated lymphocytes,... | |||
TMPK-00078 | CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
|
Human | HEK293 |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a... | |||
TMPK-00079 | CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
|
Human | HEK293 |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a... | |||
TMPK-00080 | CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
|
Human | HEK293 |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a... | |||
TMPK-00192 | B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi)
B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulat... | |||
TMPK-00193 | B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated
B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulat... | |||
TMPK-00237 | 2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated
2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated
|
Human | HEK293 |
2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 ... | |||
TMPK-00500 | CD83 Protein, Cynomolgus, Recombinant (His)
CD83 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety o... | |||
TMPK-00530 | BTLA Protein, Cynomolgus, Recombinant (His)
BTLA Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibi... | |||
TMPK-00666 | CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)
CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a... | |||
TMPK-01066 | BTLA Protein, Human, Recombinant (His & Avi)
BTLA Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibi... | |||
TMPK-01264 | B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)
B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulat... | |||
TMPY-00175 | BTLA Protein, Human, Recombinant (hFc)
BTLA Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its... | |||
TMPY-00461 | BTLA Protein, Rat, Recombinant (mFc)
BTLA Protein, Rat, Recombinant (mFc)
|
Rat | HEK293 |
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its... | |||
TMPY-00656 | 2B4/CD244 Protein, Human, Recombinant (hFc)
2B4/CD244 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
The CD244 antigen, also known as 2B4, is a cell surface glycoprotein implicated in the regulation of natural killer and T lymphocyte function. 2B4 is a member of... | |||
TMPY-01568 | 2B4/CD244 Protein, Human, Recombinant (His)
2B4/CD244 Protein, Human, Recombinant (His)
|
Human | HEK293 |
The CD244 antigen, also known as 2B4, is a cell surface glycoprotein implicated in the regulation of natural killer and T lymphocyte function. 2B4 is a member of... | |||
TMPY-01666 | RP105/CD180 Protein, Mouse, Recombinant (hFc)
RP105/CD180 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-01667 | RP105/CD180 Protein, Mouse, Recombinant (His)
RP105/CD180 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified... |