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E3 Ligase Ligand-Linker Conjugate

Cat. No. Product name CAS No. Purity Chemical Structure
T18872 (S,R,S)-AHPC-PEG5-COOH 2172820-14-1 98%
(S,R,S)-AHPC-PEG5-COOH
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC...
T18824 Thalidomide-O-C6-NH2 TFA 1957235-99-2 98%
Thalidomide-O-C6-NH2 TFA
Thalidomide-O-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].
T18817 Thalidomide-O-amido-C8-NH2 hydrochloride T18817 98%
Thalidomide-O-amido-C8-NH2 hydrochloride
Thalidomide-O-amido-C8-NH2 hydrochloride is a synthetic conjugate of an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide and a ...
T18812 Thalidomide-PEG2-C2-NH2 TFA 2097509-36-7 98%
Thalidomide-PEG2-C2-NH2 TFA
Thalidomide-O-amido-PEG3-C2-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon ligand based on Thalidomide and a 2-unit PEG linker f...
T18671 (S,R,S)-AHPC-Me-C7 ester T18671 98%
(S,R,S)-AHPC-Me-C7 ester
(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1].
T18669 (S,R,S)-AHPC-Me-C10-NH2 2376139-52-3 98%
(S,R,S)-AHPC-Me-C10-NH2
(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. Th...
T18666 (S,R,S)-AHPC-C4-NH2 2138439-53-7 98%
(S,R,S)-AHPC-C4-NH2
(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate of an E3 ligase ligand-linker, which combines the VHL ligand based on (S,R,S)-AHPC and a linker specificall...
T18820 Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride 2245697-84-9 98%
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound incorporate...
T18664 (S,R,S)-AHPC-C3-NH2 2361119-88-0 98%
(S,R,S)-AHPC-C3-NH2
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in ...
T18668 (S,R,S)-AHPC-Me-C10-Br T18668 98%
(S,R,S)-AHPC-Me-C10-Br
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker ...
T18806 Thalidomide-NH-C10-COOH T18806 98%
Thalidomide-NH-C10-COOH
Thalidomide-NH-C10-COOH (compound 6b) is a synthetic E3 ligase ligand-linker conjugate. This compound combines the Thalidomide-based von Hippel-Lindau (VHL) liga...
T13671L (S,R,S)-AHPC-Me dihydrochloride T13671L 98%
(S,R,S)-AHPC-Me dihydrochloride
(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC d...
T18826 Thalidomide-O-PEG2-propargyl 2098487-52-4 98%
Thalidomide-O-PEG2-propargyl
Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a...
T7752 (S,R,S)-AHPC-Me 1948273-02-6 99.86%
(S,R,S)-AHPC-Me
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R...
T40002 Pomalidomide-C3-NH2 hydrochloride 2154342-45-5 99.60%
Pomalidomide-C3-NH2 hydrochloride
Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
T40001 Pomalidomide-C6-COOH 2225940-50-9 99.57%
Pomalidomide-C6-COOH
Pomalidomide-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology...
T5102 TGN-020 51987-99-6 99.54%
TGN-020
TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.
T40004 Pomalidomide-C7-NH2 hydrochloride 2093387-55-2 99.36%
Pomalidomide-C7-NH2 hydrochloride
Pomalidomide-C7-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
T40008 Pomalidomide-C6-I TFA T40008 99.31%
Pomalidomide-C6-I TFA
Pomalidomide-C6-I TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technolog...
T40003 Thalidomide-NH-C6-NH2 hydrochloride 2375194-37-7 99.27%
Thalidomide-NH-C6-NH2 hydrochloride
Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
(S,R,S)-AHPC-PEG5-COOH
T18872
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC...
Thalidomide-O-C6-NH2 TFA
T18824
Thalidomide-O-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].
Thalidomide-O-amido-C8-NH2 hydrochloride
T18817
Thalidomide-O-amido-C8-NH2 hydrochloride is a synthetic conjugate of an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide and a ...
Thalidomide-PEG2-C2-NH2 TFA
T18812
Thalidomide-O-amido-PEG3-C2-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon ligand based on Thalidomide and a 2-unit PEG linker f...
(S,R,S)-AHPC-Me-C7 ester
T18671
(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1].
(S,R,S)-AHPC-Me-C10-NH2
T18669
(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. Th...
(S,R,S)-AHPC-C4-NH2
T18666
(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate of an E3 ligase ligand-linker, which combines the VHL ligand based on (S,R,S)-AHPC and a linker specificall...
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
T18820
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound incorporate...
(S,R,S)-AHPC-C3-NH2
T18664
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in ...
(S,R,S)-AHPC-Me-C10-Br
T18668
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker ...
Thalidomide-NH-C10-COOH
T18806
Thalidomide-NH-C10-COOH (compound 6b) is a synthetic E3 ligase ligand-linker conjugate. This compound combines the Thalidomide-based von Hippel-Lindau (VHL) liga...
(S,R,S)-AHPC-Me dihydrochloride
T13671L
(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC d...
Thalidomide-O-PEG2-propargyl
T18826
Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a...
(S,R,S)-AHPC-Me
T7752
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R...
Pomalidomide-C3-NH2 hydrochloride
T40002
Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
Pomalidomide-C6-COOH
T40001
Pomalidomide-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology...
TGN-020
T5102
TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.
Pomalidomide-C7-NH2 hydrochloride
T40004
Pomalidomide-C7-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
Pomalidomide-C6-I TFA
T40008
Pomalidomide-C6-I TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technolog...
Thalidomide-NH-C6-NH2 hydrochloride
T40003
Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
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