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Suritozole

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Catalog No. T8568Cas No. 110623-33-1
Alias MDL-26479

Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor

Suritozole

Suritozole

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Purity: 99.25%
Catalog No. T8568Alias MDL-26479Cas No. 110623-33-1
Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$56In StockIn Stock
5 mg$125In StockIn Stock
10 mg$190In StockIn Stock
25 mg$313In StockIn Stock
50 mg$441In StockIn Stock
100 mg$596In StockIn Stock
200 mg$791-In Stock
1 mL x 10 mM (in DMSO)$112In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.25%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor
In vivo
Suritozole is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor that enhances cholinergic function, in attenuating spatial memory deficits after traumatic brain injury in the rat.
SynonymsMDL-26479
Chemical Properties
Molecular Weight223.27
FormulaC10H10FN3S
Cas No.110623-33-1
SmilesCN1C(=NN(C)C1=S)C2=CC(F)=CC=C2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (123.17 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.4789 mL22.3944 mL44.7888 mL223.9441 mL
5 mM0.8958 mL4.4789 mL8.9578 mL44.7888 mL
10 mM0.4479 mL2.2394 mL4.4789 mL22.3944 mL
20 mM0.2239 mL1.1197 mL2.2394 mL11.1972 mL
50 mM0.0896 mL0.4479 mL0.8958 mL4.4789 mL
100 mM0.0448 mL0.2239 mL0.4479 mL2.2394 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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