CSF1R Protein, Cynomolgus, Recombinant (His)

Name: CSF1R Protein, Cynomolgus, Recombinant (His)
Brand: TargetMol
SKU: TMPK-00656
Rating: 4.5 (1 reviews)

(Synonyms: M-CSFR, MCSFR, M-CSF R, HDLS, FMSFIM2, FMS, FIM2, CSFR, CSF-1-R, CSF1R, C-FMS, CD115) Copy Product Info

Synonyms: M-CSFR, MCSFR, M-CSF R, HDLS, FMSFIM2, FMS, FIM2, CSFR, CSF-1-R, CSF1R, C-FMS, CD115

Catalog No. TMPK-00656 Copy Product Info

M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 56.3 kDa and the accession number is G7P8P1.

CSF1R Protein, Cynomolgus, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$46	7-10 days	7-10 days
10 µg	$72	7-10 days	7-10 days
20 µg	$115	7-10 days	7-10 days
50 µg	$222	7-10 days	7-10 days
100 µg	$371	7-10 days	7-10 days
200 µg	$673	7-10 days	7-10 days
500 µg	$1,490	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1. Immobilized Cynomolgus M-CSF R, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-M-CSF R Antibody, hFc Tag with the EC50 of 17.6ng/ml determined by ELISA (QC Test). 2. Cynomolgus M-CSF R, His Tag immobilized on CM5 Chip can bind Cynomolgus M-CSF, His Tag with an affinity constant of 0.889 μM as determined in SPR assay.
Description	M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 56.3 kDa and the accession number is G7P8P1.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	G7P8P1
Construction	Ile99-Pro596
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	M-CSFR, MCSFR, M-CSF R, HDLS, FMSFIM2, FMS, FIM2, CSFR, CSF-1-R, CSF1R, C-FMS, CD115
Research Background	CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region.CSF1R is tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.

Chemical Properties

Molecular Weight

56.3 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.