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Synonyms: M-CSF-R, MCSF Receptor, HDLS, FMS, FIM2, CSFR, CSF-1R, colony stimulating factor 1 receptor, C-FMS, CD115

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $44 | 7-10 days | 7-10 days | |
| 10 μg | $68 | 7-10 days | 7-10 days | |
| 20 μg | $108 | 7-10 days | 7-10 days | |
| 50 μg | $215 | 7-10 days | 7-10 days | |
| 100 μg | $359 | 7-10 days | 7-10 days | |
| 200 μg | $696 | 7-10 days | 7-10 days |
| Bioactivity | 1. Immobilized sMCSFR at 10 μg/ml (100 μl/well) can bind biotinylated human CSF1-His , The EC50 of biotinylated human CSF1-His is 32-74.8 ng/ml.
2. Measured by its ability to inhibit the human CSF-induced proliferation of M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.3-1.5 μg/mL in the presence of 3 ng/mL of rhM-CSF. |
| Description | CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | Tag Free |
| Accession Number | P07333-1 |
| Construction | The mature form of human M-CSFR (NP_005202.2) extracellular domain (Met 1-Glu 512) with quinary-aa peptide (DDDDK) at the C-terminus was expressed and purified. Predicted N terminal: Ile 20 |
| Protein Purity | > 90 % as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | M-CSF-R, MCSF Receptor, HDLS, FMS, FIM2, CSFR, CSF-1R, colony stimulating factor 1 receptor, C-FMS, CD115 |
| Research Background |
| Molecular Weight | 55.1 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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